In Switzerland, greenhouses for tomato (Solanum lycopersicum) production are inspected systematically for Tomato brown rugose fruit virus (ToBRFV) in accordance with phytosanitary regulations, by sampling symptomatic plants during routine visits. In July 2021, a suspected viral disease was reported from an 8-hectare greenhouse in the canton of Thurgau in eastern Switzerland, on a single plant in a soil-grown tomato crop (cv. Dubino). This plant exhibited light discoloured spots which were unusual for this variety and were rather reminiscent of the symptoms associated with Pepino mosaic virus (PepMV) infection.