The introduction of novel genomic tools is currently revolutionizing crop plant and livestock breeding at a fast pace. Knowledge on the genomic basis of breeding-relevant phenotypic traits combined with novel targeted breeding techniques now allows to obtain desired phenotypes much more efficiently and speed up breeding. However, the generation and interpretation of genomic data is still complicated, especially for crops with large polyploid genomes. Last year, we started several collaborations with crop and livestock breeding groups at Agroscope to develop and analyse the genomic resources required to rapidly advance their projects and to conduct fundamental research. Inspired by the resounding success of these collaborations, we propose the SPRINT project, in which we generate and analyse genomic data and develop tools to speed up breeding programs at Agroscope and analyse the efficiency and biosafety of novel breeding techniques. Connecting several groups and research fields, this project will contribute towards the modernisation of agroecological production systems and the development of urgently needed novel breeds and varieties resilient to diseases and climate change.